Remote Excitation of Neuronal Circuits Using Low-Intensity, Low-Frequency Ultrasound

Remote Excitation of Neuronal Circuits Using Low-Intensity, Low-Frequency Ultrasound

Possessing the ability to noninvasively elicit brain circuit activity yields immense experimental and therapeutic power. Most currently employed neurostimulation methods rely on the somewhat invasive use of stimulating electrodes or photon-emitting devices. Due to its ability to noninvasively propagate through bone and other tissues in a focused manner, the implementation of ultrasound (US) rep...

Low Intensity Ultrasound, Proliferation & Growth Indexes in Adult Stem Cell

LOW INTENSITY PULSED ULTRASOUND TREATMENT INCREASES RABBIT RADIAL FRACTURE HEALING

In order to study the effect of ultrasound (US) on bone healing, a complete transverse fracture was made in the right radius of adult male rabbits by a cutter. 52 rabbits were used: group I. control (n= 17): group 2. test (n:=: 15): group 3, intact (n= I) and group 4 (n= 12) who were examined only for evaluation of the cutter effects in detail. 7 animals were operated with a Gigli saw. The ...

Frequency sensitive mechanism in low-intensity ultrasound enhanced bioeffects

This study presents two novel theoretical models to elucidate frequency sensitive nuclear mechanisms in low-intensity ultrasound enhanced bioeffects. In contrast to the typical 1.5 MHz pulsed ultrasound regime, our group previously experimentally confirmed that ultrasound stimulation of anchored chondrocytes at resonant frequency maximized gene expression of load inducible genes which are regul...

Low Intensity Pulsed Ultrasound (LIPUS)

The application of ultrasound energy at much lower levels than is the current clinical norm is starting to gain ground as a therapeutic possibility. Clearly the applied energy is the same, it is the ‘dose’ which is different – most importantly, the intensity (W cm) – which is MUCH lower – typically 2 or 3 times lower than the lowest setting on most regular clinical machines, with the most commo...